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Game-Changing AI: Real-Time Gaming, Nanoscale Diagnostics, and 100M Token Models

Explore how AI is transforming real-time gaming, revolutionizing diagnostics, and setting new benchmarks in software development with Magic AI's 100M token models.

First off, I want to apologize for being MIA this past week. After nearly 400 newsletters written to date, this was the first time I decided to take a week for myself. It was much-needed, but I'm back, recharged, and ready to dive back into the latest in AI.

Today's newsletter is packed with exciting updates, from game-changing AI in gaming and healthcare to breakthroughs in software development and drug discovery. Let's get right into it!

Thanks for sticking around. I missed bringing you the latest!

Top Stories:

  1. AI Just Became Your Game Developer: The Wild Future of Real-Time Gaming

  2. AI Just Got Superpowers: Detecting Cancer and Viruses at the Nanoscale

  3. Magic AI's Game-Changing 100M Token Context Models: The Future of Software Development

  4. ActFound: The AI Model Set to Revolutionize Drug Discovery

News from the Front Lines:

  • OpenAI races to launch ‘Strawberry’ reasoning AI to boost chatbot business.

  • California's "AI Safety" bill will have global effects.

  • Agentic systems and synthetic voices: The AI job-takeover timeline.

  • A new way to build neural networks could make AI more understandable.

Tutorial of the Day:

  • Build No Code AI Agents - Step-by-step guide to building AI agents with n8n without coding.

Research of the Day:

  • Law of Vision Representation in MLLMs - A new principle linking cross-modal alignment in vision representation to the overall performance of multimodal language models.

Video of the Day:

  • Project Orion (GPT-5 Strawberry) Imminent, Already Shown To FEDS! - Analysis of OpenAI's next big leap.

Tools of the Day:

  • Clockwise, AI Ads Analyzer, SpeakHints, AgentOps, GPTEngineer, KeyMentions.

Prompt of the Day:

  • Become A Make Automation Expert - Step-by-step guidance for creating automation scenarios on Make.com.

Tweet of the Day:

  • Mckay Wrigley - Demonstrating how to generate a fully functional backend in Cursor with a single prompt.

AI Just Became Your Game Developer: The Wild Future of Real-Time Gaming

Quick Byte: 

Imagine playing a game where everything, literally everything, is generated by AI in real-time. GameNGen, a new AI-powered game engine, is taking the gaming world by storm, and it might just be the coolest thing to happen to your screen since, well, ever.

Key Takeaways:

  • AI Does the Heavy Lifting: GameNGen isn’t your run-of-the-mill game engine. It’s entirely powered by neural networks, and it's already flexing by running the classic game DOOM at over 20 frames per second. The crazy part? You can barely tell it’s not the original.

  • Training That’s Actually Fun: The engine gets its skills in two phases. First, an AI learns to play the game (so it doesn’t embarrass itself). Then, a diffusion model kicks in, predicting and generating each game frame based on the AI's past moves. It’s like the AI is playing chess with itself but on your screen.

  • Gaming’s Glow-Up: With GameNGen, the gameplay is smooth, real, and oh-so-addictive. The AI’s simulations are so good that even seasoned gamers struggle to spot the difference between real and AI-generated footage.

  • Rewriting the Rules: The future of game development might just be AI-driven. Forget coding endless lines; tweak some AI parameters, sit back, and let the magic happen. Game developers, your jobs are about to get a whole lot more interesting—or terrifying, depending on how you look at it.

The Bigger Picture:

GameNGen isn’t just another fancy tool; it’s flipping the script on how we think about game design and interactive experiences. We’re talking about a future where you don’t need a team of developers, just a powerful AI, some creative direction, and voilà—you’ve got a game. The potential is massive, from slashing development costs to opening up wild new ways to play. And this isn’t just about games. Imagine interactive movies, AI-driven virtual worlds, or apps that evolve in real time based on your input. The boundaries of what’s possible are expanding faster than ever, and GameNGen is right at the heart of it. Buckle up, because the game, literally, just changed.

AI Just Got Superpowers: Detecting Cancer and Viruses at the Nanoscale

Quick Byte: 

Researchers have developed an AI called AINU that doesn’t just diagnose; it’s peering into the microscopic world with nanoscale precision to catch diseases in their earliest stages.

Key Takeaways:

  • AI with X-Ray Vision (Sort Of): AINU, the brainchild of some seriously smart people at the Centre for Genomic Regulation and other top-tier institutions, is no ordinary AI. It uses cutting-edge microscopy techniques to analyze cell structures at a resolution that’s 5,000 times thinner than a human hair. Translation? It can see stuff no human eye—or regular microscope—ever could.

  • Cancer Detection on Steroids: The AI scans high-res images of cells and can spot cancerous changes almost immediately. We’re talking about detecting the tiniest alterations in how DNA is arranged inside cells, which could give doctors a crucial head start in treating the disease.

  • Catching Viruses Before They Strike: AINU doesn’t stop at cancer. It can also identify viral infections, like herpes simplex, just one hour after a cell gets infected. Normally, doctors have to wait for visible symptoms, but with this tech, they could start treatment way sooner.

  • The Big Picture for Stem Cells: The AI isn’t just about detecting diseases; it’s also making strides in stem cell research. AINU can pinpoint pluripotent stem cells, which are the ones that can turn into any cell in your body. This could make stem cell therapies safer, faster, and more reliable—plus, it might even help reduce the need for animal testing.

The Bigger Picture:

This AI isn’t just another cool tool; it’s a game-changer. We’re entering an era where diseases could be caught and treated before they become life-threatening, all thanks to AI. Sure, the tech isn’t clinic-ready yet—those high-res images require some pretty specialized (and expensive) equipment. But the potential here is huge. Imagine a future where your regular check-up includes an AI scan that can catch cancer or viruses when they’re just getting started. That’s where we’re headed, and it’s going to revolutionize how we think about healthcare.

Magic AI's Game-Changing 100M Token Context Models: The Future of Software Development

Image Source: Magic

Quick Byte: 

Imagine your AI model not just remembering bits and pieces but holding onto entire libraries of code, all at once. Magic AI is pushing the limits of what’s possible with their new ultra-long context models, and they're not just talking big; they're delivering. These models, capable of handling up to 100 million tokens at once, are about to redefine how software development gets done.

Key Takeaways:

  • What’s the Big Deal? Until now, AI models had short-term memory—enough to handle a few lines of code or a single task. But Magic's new LTM (Long-Term Memory) models can process 100 million tokens in context. That’s like having all your code, documentation, and libraries right there, ready for the AI to access during inference. Imagine an AI that doesn’t just guess but knows because it’s seen every line of your codebase.

  • Why It Matters: This isn’t just a cool experiment. Magic is laser-focused on software development. Think about code synthesis, debugging, or even creating new features—if your AI has everything it needs in context, it can make better, faster decisions. This could be a massive game-changer for developers, making AI a real partner in the coding process.

  • How They’re Doing It: Magic’s new evaluation method, HashHop, eliminates the shortcuts that other models rely on. By using random and incompressible hashes, the AI has to really think (well, compute) to complete tasks. This is like training for a marathon with a weighted vest—you’re going to be stronger when it counts.

  • Real-World Applications: Magic isn’t just theorizing. They’ve already trained LTM-2-mini, a model that can handle 100 million tokens—a context window big enough to fit 10 million lines of code or over 750 books. They’ve even managed to make a custom GUI framework and a password strength meter without any human help, showcasing what’s possible when you combine ultra-long context with real-time learning.

  • Big Tech Backs It: Magic is teaming up with Google Cloud and NVIDIA to build supercomputers that can handle these massive models. With new funding from big names like Eric Schmidt and Sequoia, Magic is on a mission to scale up and push the boundaries of what AI can do.

The Bigger Picture:

Magic AI is flipping the script on what we expect from AI models. With their ultra-long context windows, the idea of training once and relying on memory is out the window. This is about giving AI the tools to think on its feet, making it a more powerful ally in software development and beyond.

ActFound: The AI Model Set to Revolutionize Drug Discovery

Quick Byte: 

Forget what you know about traditional drug development. ActFound, a new AI model, is stepping into the ring, promising to make the process faster, cheaper, and more accurate. This AI is outperforming existing models and potentially saving pharmaceutical companies millions.

Key Takeaways:

  • What’s the Big Deal? Drug development is notoriously slow, expensive, and resource-intensive. Enter ActFound, a cutting-edge AI model developed by scientists from Peking University, the University of Washington, and INF Technology Shanghai. ActFound is designed to predict the bioactivity of compounds, a critical step in drug discovery. This AI model outperforms traditional methods and even rivals Free-Energy Perturbation (FEP), a computational technique known for its accuracy but also for its high cost and complexity.

  • Why It Matters: In the world of pharmaceuticals, time is money—and ActFound could save a lot of both. Unlike traditional methods that require massive computational power and expensive lab equipment, ActFound can operate with fewer data points and still deliver highly accurate results. This could significantly reduce the time and cost of bringing new drugs to market, making it a game-changer for both the industry and patients waiting for new treatments.

  • How It Works: ActFound leverages two advanced machine learning techniques—meta-learning and pairwise learning—to tackle the challenges of bioactivity prediction. Meta-learning allows the model to predict properties of unmeasured compounds with limited labeled data, while pairwise learning focuses on the relative differences between compounds rather than absolute values. This dual approach enables ActFound to generalize across different assays and predict bioactivity with impressive accuracy.

  • Real-World Impact: The researchers tested ActFound on six real-world bioactivity datasets, and the results were nothing short of impressive. The model outperformed nine competing AI models in predicting bioactivity within a given domain and showed strong cross-domain prediction capabilities. In a case study focusing on cancer drugs, ActFound outshone other models, proving its potential as a powerful tool in the fight against diseases.

  • What’s Next? While ActFound is still in the research phase, its success could pave the way for widespread adoption in drug development. With the pharmaceutical industry already turning to AI to cut down on development time, ActFound could become a cornerstone in this new era of machine-learning-driven drug discovery.

The Bigger Picture: 

The pharmaceutical industry is on the brink of a major transformation, and AI is leading the charge. ActFound isn’t just another AI model; it represents a fundamental shift in how we approach drug discovery. By combining cutting-edge machine learning techniques with real-world applications, ActFound could help scientists identify new drugs faster and more efficiently than ever before. As AI continues to evolve, we’re looking at a future where the process of bringing life-saving drugs to market could be faster, more cost-effective, and more accessible. This is just the beginning, and the possibilities are endless.

Build No Code AI Agents

Authors: Shijia Yang, Bohan Zhai, Quanzeng You, Jianbo Yuan, Hongxia Yang, Chenfeng Xu

Institutions: Stanford University, UC Berkeley

Summary: The "Law of Vision Representation" in Multimodal Large Language Models (MLLMs) establishes a groundbreaking principle that links cross-modal alignment and correspondence in vision representation to the overall performance of MLLMs. By introducing the Cross-modal Alignment and Correspondence score (AC score), the authors quantify how well different vision representations perform in relation to MLLM benchmarks. The study demonstrates that the AC score is linearly correlated with model performance, which allows researchers to predict the optimal vision representation without repeatedly fine-tuning the language model, significantly reducing computational costs by 99.7%.

Why This Research Matters: As the demand for AI systems that can understand and interpret visual data alongside textual information grows, ensuring that the underlying vision representation in MLLMs is optimized becomes crucial. This research provides a systematic approach to selecting the best vision representation, eliminating the guesswork and high costs traditionally associated with this process. The "Law of Vision Representation" could revolutionize how MLLMs are developed, making them more efficient and effective in real-world applications.

Key Contributions:

  • AC Score Introduction: A novel metric that quantifies the effectiveness of vision representation in MLLMs, with a strong correlation to model performance.

  • Cost Reduction: The study outlines a method to drastically reduce computational costs by selecting the optimal vision representation without needing to fine-tune the language model for each change.

  • Empirical Validation: Extensive experiments across 13 vision representation settings and eight benchmarks validate the linear relationship between the AC score and model performance.

Use Cases:

  • Autonomous Systems: Enhances the ability of AI systems in autonomous vehicles to accurately process and understand visual data in real-time.

  • Healthcare Imaging: Improves the efficiency and accuracy of AI-driven diagnostics by selecting the optimal vision representation for analyzing medical images.

  • Robotics: Enables more precise visual interpretation in robots, enhancing their ability to interact with and understand their environments.

Impact Today and in the Future:

  • Immediate Applications: The AC policy can be immediately applied to optimize current MLLMs, significantly enhancing their performance across various tasks that involve visual data.

  • Long-Term Evolution: This research lays the foundation for more advanced, cost-effective, and efficient MLLMs that can handle increasingly complex multimodal tasks.

  • Broader Implications: By providing a clear methodology for selecting vision representations, this study will drive the development of more capable AI systems, influencing fields ranging from autonomous driving to complex visual reasoning.

Clockwise - Clockwise works across entire teams and companies to craft the perfect schedules, all based on preferences. No more mind reading or trying to conjure time out of nowhere.

AI Ads Analyzer - Get a detailed report of visuals, copy, and hook only by uploading your ad, and adding a landing page!

SpeakHints - AI-powered real-time speech copilot, continously showing you private suggestions on what to say next.

AgentOps - Industry leading developer platform to test and debug AI agents.

GPTEngineer - Build for the web 10x faster. Chat with AI to build web apps. Sync with GitHub. One-click deploy.

KeyMentions - Tracks your brand and keywords and notifies you at the exact moment a relevant discussion is taking place.

Become A Make Automation Expert:

Role:  

Act like an expert automation architect with a deep understanding of Make.com (formerly Integromat). You have extensive experience turning user ideas into effective automation workflows that improve efficiency and streamline operations.  

Objective:  

Guide the user in creating a complete automation scenario on Make.com by providing step-by-step instructions and tasks. The user will input their specific idea, and you will assist them in building and optimizing the scenario.  

Context:  

Describe Your Automation Idea:  Example: "I want to automatically send a welcome email to new customers who sign up on my website." Your Idea: [User Input Here]  List the Apps and Services Involved:  Example: "Mailchimp, Google Sheets, Shopify." Your Apps/Services: [User Input Here]  Define the Desired Outcome:  Example: "Send a personalized email with a discount code when a new user is added to the Mailchimp list." Your Desired Outcome: [User Input Here]  

Instructions and Tasks:  

Task 1: Clarify Your Automation Idea  Review the idea you’ve inputted. Ensure it is specific and actionable. Example: "Automatically add new Shopify customers to a Google Sheet and send them a confirmation email." If needed, refine your idea to be more precise.  

Task 2: Identify and Set Up Apps and Services  Confirm the apps and services you’ll be using in the scenario. If you’re unsure, consider common pairings: E-commerce and CRM: Shopify + HubSpot Communication: Gmail + Slack Log in to Make.com and ensure these apps are connected.  

Task 3: Create a New Scenario  In Make.com, start by creating a new scenario. Select the app that will trigger the scenario (e.g., "New order in Shopify"). Example: If your trigger is “New order in Shopify,” select Shopify as the trigger app and configure it to start the scenario when a new order is placed.  

Task 4: Configure Triggers and Actions  Add the necessary actions that follow your trigger. For example: "Add new customer details to Google Sheets." "Send a confirmation email via Gmail." Map data from the trigger to the actions using Make.com’s data mapping tools.  

Task 5: Apply Filters and Conditions  Set up filters to narrow down when the scenario should run. Example: Only send an email if the order value is over $50. Add conditions based on your needs.  

Task 6: Test the Scenario  Run the scenario using test data to ensure it works correctly. Review the scenario logs to check for errors or unexpected behavior. Example: If the email doesn’t send, verify the data mapping and conditions.  

Task 7: Optimize and Finalize  Adjust the scenario for efficiency, such as reducing unnecessary steps. Consider adding error handling (e.g., send a notification if the email fails to send). Example: Combine steps to reduce the number of operations.  

Task 8: Activate and Monitor  Once satisfied, activate the scenario in Make.com. Set up alerts or notifications to monitor its performance. Example: Receive a Slack message if an error occurs.  

Task 9: Iterate and Improve  Regularly review the scenario to ensure it meets your needs. Make improvements or add new features as your business requirements evolve.  

Final Step:  Take a deep breath and work on this problem step-by-step.